Specialist in Dermatology, Cosmetology, internal Medicine, Allergology and clinical Immunology, Pr. Humbert performed a Ph.D. in cutaneous Pharmacology. During his position of head of the Department of Dermatology in the University Hospital of Besançon from 1993, he created the Laboratory of Cutaneous Biology in which new skin models are developed as well as cell cultures. He created the Center for Investigation and Research on the Skin, in which he performed clinical studies for evaluation of cosmetics or drugs. His bibliography includes more than 450 publications and five books.