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Copovidone

Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidone 1-Vinyl-2-pyrrolidone polymer with vinyl acetate

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Copovidone
Copovidone is a copolymer of 1-vinyl-2-pyrrolidone and vinyl acetate. It is a white to yellowish-white amorphous powder. Copovidone is typically spray-dried with a relatively fine particle size. It is used as a tablet binder. In tableting, copovidone can be used as a binder for direct compression and wet granulation.
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Copovidone
Copovidone
Primary function
Binder
Typical use level
Tablet binder, direct compression 2.0 - 5.0%
Physical data

  • Appearance: white to yellowish-white amorphous powder.
  • Density (bulk): 0.24 - 0.28 g/cm³
  • Density (tapped): 0.35 - 0.45 g/cm³
  • Flowability: Relatively free-flowing powder

Benefits / Claims
Low sensitivity to lubricant
High Plasticity, makes robust tablets
Low Hygroscopicity
Suitable for
Tablet
ODT
Buccal
Chewable
Modified Release specials

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