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Croscarmellose Sodium

Cross-linked sodium carboxymethyl cellulose XLCMC CCS

Croscarmellose Sodium
It appears as long, narrow fibrous particles. Croscarmellose works primarily by wicking or capillary action and also swells as it hydrates. A non-GMO grade made using wood cellulose is available for formulations where label claims are important.
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Croscarmellose Sodium
Croscarmellose Sodium
Primary function
Superdisintegrant
Typical use level
1 - 3% (direct compression), 2 - 4% (wet granulation: 1 - 2% intra granularly, 1 - 2% extra granularly)
Physical data

  • Occurs as an odourless, white or greyish white powder.
  • Bulk density: 0.53 g/cm³
  • Particle size: 25 - 55 µm (d50)

Benefits / Claims
Highly effective and efficient disintegrant with lower use level compared to other disintegrants. Rapid water uptake to aid disintegration and reduce impaction in teeth during chewing.
Suitable for
Tablet
Hard Gel Capsules
ODT
Buccal
Chewable

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