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Crospovidone

1-Ethenyl-2-pyrrolidinone homopolymer Cross-linked povidone XLPVP

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Crospovidone
Crospovidone is a water-insoluble synthetic cross-linked homopolymer. It is used as a tablet disintegrant in the direct compression or wet - and dry-granulation process. Crospovidone is white to creamy-white, finely divided, free-flowing, practically tasteless, hygroscopic powder. Larger particles provide faster disintegration than smaller particles.
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Crospovidone
Crospovidone
Primary function
Disintegrant
Typical use level
Tablet disintegrant used at 2 - 5% concentration in tablets prepared by direct compression or wet and dry granulation methods
Physical data

  • Appearance: white to creamy-white hygroscopic powder
  • Density: 1.22 g/cm³
  • Flowability: Free-flowing
  • Solubility: Practically insoluble in water

Benefits / Claims
High capillary activity and hydration capacity with little tendency to form gels
pH independent disintegrant performance for active delivery throughout the GIT
Suitable for
Tablet
Hard Gel Capsules
ODT
Buccal
Chewable

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