1-Ethenyl-2-pyrrolidinone homopolymer Cross-linked povidone XLPVP
Crospovidone is a water-insoluble synthetic cross-linked homopolymer. It is used as a tablet disintegrant in the direct compression or wet - and dry-granulation process. Crospovidone is white to creamy-white, finely divided, free-flowing, practically tasteless, hygroscopic powder. Larger particles provide faster disintegration than smaller particles.
|Typical use level|
Tablet disintegrant used at 2 - 5% concentration in tablets prepared by direct compression or wet and dry granulation methods
|Benefits / Claims|
High capillary activity and hydration capacity with little tendency to form gels
Can be used intra- and extra-granularly for improved active release
pH independent disintegrant performance for active delivery throughout the GIT