Crystallisation inhibitor
Crystallisation of drug reduces the bioavailability of the drug resulting in reduction of efficacy of formulation. Crystallisation inhibitors prevent the crystallisation of the drug by increasing viscosity or by formation of hydrogen bonds with the drug.
Examples: Povidone grades, Copovidone grades
Examples: Povidone grades, Copovidone grades
Crystallisation inhibitor
Crystallisation inhibitor | |
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Primary function | Crystallisation inhibitor |
Typical use level | In creams and lotions, levels can be as low as 3% w/w. |
Benefits / Claims | Prevent further growth of suspended particles in case of creams/lotions containing dispersed drug. |
Suitable for | |