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Downstream

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Downstream
Downstream processing consists of various unit-operations in which the product is isolated and purified, producing a bulk drug substance. 
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Downstream

pH modifiers

  • Zwitterion buffers
  • Inorganic salts
  • Sodium hydroxide
  • Amino Acids

Protein stabilising agents

  • Carbohydrates
  • Polyols
  • Hydroxypropyl betadex

Surfactants

  • Polysorbates

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