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CAS: 33419-42-0


Etoposide is a semisynthetic derivative of podophyllotoxin, a natural product found in the roots and rhizomes of plants of the Podophyllum genus. Etoposide is used in the treatment of certain neoplastic diseases. It may be administered either intravenously or orally.

Initial US FDA approval: 1983

It is on the World Health Organization model list of essential medicines.

Therapeutic group
Antineoplastic agents, podophyllotoxin derivatives
ATC code: L01CB01

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