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Hypromellose AS

Hydroxypropyl methylcellulose-acetate succinate (HPMC-AS)

Hypromellose AS
Hydroxypropyl methylcellulose-acetate succinate dissolves into various organic solvent and has relatively low glass transition temperature. Finer particles are used as aqueous dispersions whereas granular grades are used in organic solutions for coating processes. Can be applied as a polymer in the multiparticulate system. 
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Hypromellose AS
Hypromellose AS
Primary function
Polymer for modified release
Physical data
  • Appearance: white to slightly yellow-coloured powder or granule with
    faint odour, tasteless.
  • Density: ≈ 1.30 g/cm³
  • Tg: 120 °C
Benefits / Claims
Used for targeting of drug release at specific gastro-intestinal site.
Suitable for

Modified Release specials
Bioavailability enhancement

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