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Hypromellose

Cellulose, 2- hydroxypropyl methyl ether Hydroxypropyl methyl cellulose (HPMC)

Hypromellose
Hypromellose is widely used in pharmaceuticals formulations. It is described as partly O-methylated and O-(2-hydroxypropylated) cellulose. Hypromellose is available in several grades that can vary in viscosity and extent of substitution. In the modified release oral solid dosage, Hypromellose can be applied as the hydrophilic matrix due to the fact it forms a gel upon contact with water/or fluid gastric.
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Hypromellose
Hypromellose
Primary function
Polymer for modified release
Typical use level
Generally, 20% is the minimum use level recommended to achieved sustained release
Physical data

  • Appearance: odourless and tasteless, white or creamy-white fibrous or granular powder.

Benefits / Claims
Well-recognized material
Good stability
Different grades available (flexibility on formulation)
Suitable for
Tablet
Buccal
Chewable
Oral Syrup
Oral Solutions
Lotion
Modified Release specials

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