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Hypromellose

Cellulose, 2- hydroxypropyl methyl ether Hydroxypropyl methyl cellulose (HPMC)

Hypromellose
Hypromellose (HPMC) is widely used in pharmaceuticals formulations. It is described as partly O-methylated and O-(2-hydroxypropylated) cellulose. Hypromellose is available in several grades that can vary in viscosity and extent of substitution. In oral solid forms like tablets, HPMC is primarily used as a binder.
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Hypromellose
Hypromellose
Primary function
Binder
Typical use level
Concentrations between 2% and 5% w/w may be used as a binder in wet - granulation and dry - granulation
Physical data

  • Appearance: odourless and tasteless, white or creamy-white fibrous or granular powder.

Benefits / Claims
Well-recognized material
Good stability
Soluble in cold water (easy to use in process)
Different grades available (flexibility on formulation)
Suitable for
Tablet
Buccal
Chewable
Oral Syrup
Oral Solutions
Lotion
Modified Release specials

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