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Lactose

Lactose, Monohydrate Lactose, Anhydrous Lactose, Spray-Dried Lactose, Agglomerated Lactose, Milled

Lactose
Lactose is the disaccharide of galactose and glucose. It is widely used as a filler and diluent in oral solid dosage forms such as tablets and capsules. There are several lactose grades available, which vary physically and functionally depending manufacturing process. Spray-dried and agglomerated as well as anhydrous lactose are favoured for direct compression tablet manufacture.
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Lactose
Lactose
Primary function
Filler/ Diluent
Typical use level
10 - 90%
Physical data

  • Appearance: White to nearly white crystalline particles or powder in various isomeric forms depending on crystallization and drying conditions.
  • Soluble in water
  • Specific rotation: +54.4° - 55.9°

Benefits / Claims
Formulation flexibility due to availability of different lactose grades. Deforms by brittle fracture and is a good compliment to plastically deforming formulation ingredients.
Suitable for
Tablet
Hard Gel Capsules
ODT
Buccal
Chewable
Modified Release specials
Dry-powder inhaler

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