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Lactose, Monohydrate Lactose, Anhydrous Lactose, Spray-Dried Lactose, Agglomerated Lactose, Milled

Lactose is the disaccharide of galactose and glucose. It is widely used as a filler and diluent in oral solid dosage forms such as tablets and capsules. There are several lactose grades available, which vary physically and functionally depending manufacturing process. Milled lactose is typically used in wet granulation. Milled, spray-dried, and agglomerated as well as anhydrous lactose are well suited for dry granulation.
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Primary function
Filler/ Diluent
Typical use level
10 - 90%
Physical data

  • Appearance: White to nearly white crystalline particles or powder in various isomeric forms depending on crystallization and drying conditions.
  • Soluble in water
  • Specific rotation: +54.4° - 55.9°

Benefits / Claims
Formulation flexibility due to availability of different lactose grades. Deforms by brittle fracture and is a good compliment to plastically deforming formulation ingredients.
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