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Low-substituted Hydroxypropyl Cellulose

Cellulose, 2-hydroxypropyl ether (low-substituted) L-HPC

Low-substituted Hydroxypropyl Cellulose
L-HPC is a low-substituted hydroxypropyl ether of cellulose. It is widely used in two-piece capsules. L- HPC is mainly used as a disintegrant and/or binder depending on capsule filing process. In addition, it also can also be used as a diluent.
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Low-substituted Hydroxypropyl Cellulose
Low-substituted Hydroxypropyl Cellulose
Primary function
Disintegrant, binder and diluent
Typical use level
5 - 20% (depending on grade selection and/or application)
Physical data

  • Appearance: white to yellowish white hygroscopic powder or granules
  • Tasteless
  • Insoluble in water
  • Bulk density: 0.28 - 0.48 g/cm³
  • Degree of substitution: 8 - 14%

Benefits / Claims
L-HPC wicks media into the capsule to wet the contents and assist in expelling the contents from the capsule body, facilitating active release.
Suitable for
Tablet
Hard Gel Capsules
ODT
Buccal
Chewable

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