Mannitol
Mannitol is commonly used in pharmaceutical formulations. It is primarily used as a filler/ diluent. It can be applied in the direct compression and wet granulation process. In addition, in ODT and chewable tablets, Mannitol is used due to characteristics such as sweetness and good mouthfeel, which is desired in these types of formulations.
Mannitol
Mannitol | |
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Primary function | Filler/ Diluent |
Typical use level | 10 - 90% |
Physical data |
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Benefits / Claims | Not hygroscopic: possibility to use with moisture-sensitive active ingredients Freely soluble with rapid dissolution for fast active release Sweetness and cooling effect provides excellent organoleptic properties |
Suitable for | |