Polyethylene glycols or PEGs are water-soluble polymers that are used in many pharmaceutical formulations. In topical formulations like creams, lotions and gels, they can be used as humectants and cosolvents. Higher molecular weight PEGs can be evaluated as rheology modifiers/viscosifiers in topical dosage forms. In oral applications, PEGs can be evaluated as solubilisers and viscosifiers. In OSDs, higher molecular weight PEGs can impart plasticity to granules, enhance the effectiveness of binder and can be used as lubricants for tablets. In softgel capsules, PEGs can be used as plasticisers to make the shell pliable and less brittle.
|Typical use level|
20 - 30 %
|Benefits / Claims|
PEG addition as a plasticiser makes the soft gelatin capsule elastic, overcome brittleness of films, increase impact resistance of film coating.