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Polyoxyethylene Sorbitan Fatty Acid Esters

Polysorbates are a series of partial fatty acid esters of sorbitol and its anhydrides copolymerized with approximately 20, 5, or 4 moles of ethylene oxide for each mole of sorbitol and its anhydrides
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Primary function
Solubiliser/ co-emulsifier
Typical use level
1 - 40%
Physical data

  • Depend on grades (liquid, solid), type of substituents and application

Benefits / Claims
Good solvent and emulsifying capabilities for poorly water soluble drugs.
They have been found to be useful in improving the oral bioavailability of drug molecules that are substrate for P-glycoprotein.
Suitable for

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