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Propylene glycol monolaurate

1,2- Propanediol monolaurate

Propylene glycol monolaurate
It is an excellent solubiliser for poorly soluble drugs. It also finds use as a penetration enhancer and as a co-emulsifier for microemulsions. Being oily in nature, it can also be used as an emollient.
Propylene glycol monolaurate
Propylene glycol monolaurate
It is listed in the IID. As an emollient, its level can vary from 1 - 5% w/w.

  • Appearance at 20°C: Clear, colourless or slightly yellow oily liquid
  • C12 fatty acid: ≥95.0%
  • Mixture of the propylene glycol mono and diester of lauric acid.
  • Type I Propylene glycol monolaurate contains min. of 45% monoesters, while Type II contains 90% monoesters.
  • HLB: 4.5

Excellent solubiliser for poorly soluble drugs. It is a penetration enhancer, co-emulsifier.

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