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Propylene glycol monocaprylate

Propylene glycol monocaprylate

Propylene glycol monocaprylate
It is an excellent solubiliser for poorly soluble drugs. It also finds use as a co-emulsifier for microemulsions. Used as a carrier in soft and hard gelatin capsules.
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Propylene glycol monocaprylate
Propylene glycol monocaprylate
Primary function
Solubiliser/ co-emulsifier
Typical use level
As a filler in soft gel capsules could be used at 20 to 40%.As per IID listing for oral tablets MDE is 24mg
Physical data

  • Appearance: clear liquid
  • HLB: 5 - 6
  • C8 fatty acid: 98% min
  • Mixture of the propylene glycol mono and diester of caprylic acid.
  • Type I Propylene glycol caprylate contains min. of 55% monoesters, while Type II contains 90% monoesters.

Benefits / Claims
Co-emulsifier for microemulsions. Excellent solubiliser for poorly soluble drugs
Suitable for
Cream/ Emulsion
Softgel Capsules
Gel
Lotion

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