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Propylene glycol monocaprylate

Propylene glycol monocaprylate

Propylene glycol monocaprylate
It is an excellent solubiliser for poorly soluble drugs. It also finds use as a penetration enhancer and as a co-emulsifier for microemulsions. Being oily in nature, it can also be used as an emollient.
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Propylene glycol monocaprylate
Propylene glycol monocaprylate
Primary function
Penetration enhancer
Typical use level
For gels, as a penetration enhancer, it can be used in the range of 1 - 3 % w/w.
Physical data

  • Appearance: clear liquid
  • HLB: 5 - 6
  • C8 fatty acid: 98% min
  • Mixture of the propylene glycol mono and diester of caprylic acid.
  • Type I Propylene glycol caprylate contains min. of 55% monoesters, while Type II contains 90% monoesters.

Benefits / Claims
Possesses antimicrobial activity. Excellent solubiliser for poorly soluble drugs. Acts as an emulsifier and co-emulsifier and can be used as an emollient.
Suitable for
Cream/ Emulsion
Softgel Capsules
Gel
Lotion

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