Spironolactone is an aldosterone antagonist acting both as a diuretic and as an antihypertensive drug. It is indicated to treat a number of conditions including heart failure, hypertension, oedema associated with hepatic cirrhosis or nephrotic syndrome and hyperaldosteronism.
Spironolactone is on the World Health Organization model list of essential medicines.
Cardiovascular system, diuretics, potassium-sparing agents
ATC code: C03DA01