In topical formulations like creams, lotions and gels, stabilisers can be antioxidants and chelating agents. The stabilizers are added to the formulation to prevent or minimize degradation of sensitive API. In softgel capsules, stabilisers help prevent or minimize sticking, tacking, softening and premature dissolution of the capsule shell. They also minimise oxidation or degradation of the active ingredient fill or gelatin shell.

Antioxidants

• dL- Alpha tocopherol
• 
  Butylated hydroxyanisole
• 
  Butylated hydroxytoluene
• 
  Sodium metabisulphite
• 
  Propyl gallate
• 
  Sodium sulphite

Chelating agents

• Edetate Sodium
• 
  Edetate Disodium
• 
  Edetate Calcium Disodium