Wetting agent
Dissolution of the dry powder in hard gel capsules requires the displacement of the air surrounding the powder. To enable this displacement, a wetting agent is added, which reduces interfacial tension between API and dissolution medium, thus accelerating the dissolution of the particles. A wetting would reduce the contact angle leading to wetting and spreading of liquid over the particle
Wetting agent
| Wetting agent | |
|---|---|
| Primary function | Wetting agent |
| Typical use level | 1 - 2% |
| Physical data | Sodium Lauryl Sulfate
|
| Benefits / Claims | Sodium lauryl sulfate, which is a commonly used wetting agent for hard capsule formulations is effective in both alkaline and acidic conditions. |
| Suitable for | |