Dissolution of the dry powder in hard gel capsules requires the displacement of the air surrounding the powder. To enable this displacement, a wetting agent is added, which reduces interfacial tension between API and dissolution medium, thus accelerating the dissolution of the particles. A wetting would reduce the contact angle leading to wetting and spreading of liquid over the particle
|Typical use level|
1 - 2%
Sodium Lauryl Sulfate
|Benefits / Claims|
Sodium lauryl sulfate, which is a commonly used wetting agent for hard capsule formulations is effective in both alkaline and acidic conditions.