Patient-centric design of topical medicines - The IMCD approach

Past Event

About the Webinar

Non-adherence to treatment is universally recognised as a public health problem. The annual cost to the United States health care system due to non-adherence is estimated to be around $300 billion. With topical medications, adherence rates decline to 32% over eight weeks in atopic dermatitis and 51% in psoriasis. Non-adherence leads to sub-optimal health outcomes, lower quality of life, and ultimately higher healthcare costs.

One of the key factors driving patient adherence is the patient-friendliness of topical formulations. For topicals, this aspect is directly linked to the cosmetic and galenic properties of the formulation, like the smell and the appearance, the (after)feeling on the skin (greasy, tacky, shiny) but also the time needed for the application as well as convenience of application (spreadability, absorption time etc.). The vehicle used is mainly driving these aesthetic parameters, while the formulation type will influence the convenience and application time.

One of the possible strategies to improve topical treatment adherence is the implementation of patient-centric drug product design. IMCD is developing solution concepts taking the target product profile (TPP) into account. Join our webinar where we share the reasonings behind the proper choice of topical ingredients, vehicles, and dosage forms. Following the TPP for dry skin and atopic dermatitis, we have developed patient-friendly mucopolysaccharide polysulfate (MPS) and pimecrolimus creams. By using innovative excipients, not only we have improved the stability of a metronidazole vaginal gel but formulated it into a vaginal spray with proven mucoadhesive efficacy.  Join us in this webinar find out more!

About the presenters

Kristina Kannheiser - US

Kristina brings over ten years of formulation experience, specializing in advancing products from theoretical concept to commercial launch. She is passionate about assisting customers with formulation trouble shooting from bench to full-scale production and every stage in between. Kristina holds a BS in Chemistry as well as a MS in Cosmetic Science. Her research and training interests include increasing patient compliance as well as API efficacy by examining product rheology, skin penetration technology, and sensory properties. In addition to her industry roles, Kristina is an adjunct professor at Rutgers University teaching graduate-level science classes.

Abhishek Shukla - APAC

A dedicated contributor to the topical ingredients field, with a solid twelve plus years of experience, including 5.5 years at IMCD. Abhishek Shukla, Sr. Product manager at IMCD is passionate about driving innovation and striving for improved patient compliance.

If you missed this event, you can log in to MyIMCD to watch the recorded webinar.