Known for their convenience, tablets are the most popular solid oral dosage form preferred by both patients and manufacturers alike. Out of the commonly utilised main processing methodologies, direct compression (DC) is favoured. However, DC formulations typically require multiple excipients to fulfil flowability, compressibility, disintegration, and lubrication requirements. Co-processed excipients, which combine two or more functional materials into a single ingredient, can be used to overcome these formulation challenges through their enhancement of the resulting material’s performance and processability.